FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL
(A Peer Review Journal)
e–ISSN: 2408–5162; p–ISSN: 2048–5170
keywords: Phytochemicals, antimicrobial, activity, extracts, Leea guineensis
The phytochemical screening and antimicrobial properties of the leaf extracts of Leea guineensis was studied. A number of solvents and solvent-mixtures were used to assess the most effective solvent type that is recommended for the extraction of the active components of this plant. Two extraction methods were employed: cold and Soxhlet extraction. The phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, saponins, and cardiac glycosides in all the samples of ethanol and hexane/acetone/methanol mixture extracts. The antimicrobial test results revealed that the plant extracts exhibited efficacy against a number of microbes (Eschericha coli, Staphylococcus aureus, Baccillus substillus, Streptococus pneumonia, Psudomonas aeroginosa and Candidas alblican) that were used in the study by exhibiting clear zones of inhibition against these microbes. The finding of this study recommends the use of either ethanol as a single solvent or a solvent system with a mixture of hexane/acetone/methanol with increasing polarities.
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